Disulfiram USP is a drug that has been given FDA approval to treat alcoholism. It functions by obstructing the body ability to process alcohol. When this formulation is taken with alcohol, unpleasant bodily effects such nausea, vomiting, headaches, and flushing occur. These side effects are designed to discourage people from drinking while receiving alcohol addiction therapy. Disulfiram USP aid in treating chronic alcoholism. It should be taken as per doctor guidance. It one of three medications recognised by the Federal Drug Administration (FDA) for the treatment of alcoholism. In patients with adequate professional care, it is a second-line choice.